siRNA, Anti-TMEM116, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51310WQ-2OMe)

The product SIRGT51310WQ-2OMe is a type of small interfering RNA (siRNA) that targets TMEM116 gene and regulates the expression of gene. The siRNA interferes with the expression of TMEM116 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001193453.1
Purification HPLC
Target Gene
Gene ID 89894
Uniprot ID Q8NCL8
Sub Cat Target Species Modification Scale  
SIRGT52310WQ-2F TMEM116 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53310WQ-2MOE TMEM116 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54310WQ-LNA TMEM116 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51310WQ-RB TMEM116 Human Ribo-modified Inquiry
SIRGT52310WQ-BB TMEM116 Human Backbone-modified Inquiry

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