siRNA, Anti-TMEM132B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT62228WQ-2F)
The product SIRGT62228WQ-2F is a type of small interfering RNA (siRNA) that targets TMEM132B gene and regulates the expression of gene. The siRNA interferes with the expression of TMEM132B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001286219.1 |
| Related Diseases | Intracranial Aneurysm |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT64228WQ-LNA | TMEM132B | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT86744WQ-2OMe | Tmem132b | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT87744WQ-2F | Tmem132b | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT88744WQ-2MOE | Tmem132b | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT89744WQ-LNA | Tmem132b | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT61228WQ-RB | TMEM132B | Human | Ribo-modified | ||
| SIRGT86744WQ-RB | Tmem132b | Mouse | Ribo-modified | ||
| SIRGT62228WQ-BB | TMEM132B | Human | Backbone-modified | ||
| SIRGT87744WQ-BB | Tmem132b | Mouse | Backbone-modified |
