siRNA, Anti-TMEM170B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66449WQ-2OMe)

The product SIRGT66449WQ-2OMe is a type of small interfering RNA (siRNA) that targets TMEM170B gene and regulates the expression of gene. The siRNA interferes with the expression of TMEM170B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001100829.2
Related Diseases Orofacial Cleft 1
Purification HPLC
Target Gene
Gene ID 100113407
Uniprot ID Q5T4T1
Sub Cat Target Species Modification Scale  
SIRGT67449WQ-2F TMEM170B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68449WQ-2MOE TMEM170B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69449WQ-LNA TMEM170B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT66449WQ-RB TMEM170B Human Ribo-modified Inquiry
SIRGT67449WQ-BB TMEM170B Human Backbone-modified Inquiry

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