siRNA, Anti-TRMT10B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56003WQ-2OMe)

The product SIRGT56003WQ-2OMe is a type of small interfering RNA (siRNA) that targets TRMT10B gene and regulates the expression of gene. The siRNA interferes with the expression of TRMT10B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001286950.1
Alternative Names RG9MTD3; bA3J10.9
Related Diseases Combined Oxidative Phosphorylation Deficiency 30
Purification HPLC
Target Gene
Gene ID 158234
Uniprot ID Q6PF06
Sub Cat Target Species Modification Scale  
SIRGT57003WQ-2F TRMT10B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58003WQ-2MOE TRMT10B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT59003WQ-LNA TRMT10B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT56003WQ-RB TRMT10B Human Ribo-modified Inquiry
SIRGT57003WQ-BB TRMT10B Human Backbone-modified Inquiry

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