siRNA, Anti-TTL, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT59807WQ-LNA)

The product SIRGT59807WQ-LNA is a type of small interfering RNA (siRNA) that targets TTL gene and regulates the expression of gene. The siRNA interferes with the expression of TTL gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_153712.4
Related Diseases Joubert Syndrome 1
Purification HPLC
Target Gene
Gene ID 150465
Uniprot ID Q8NG68
Sub Cat Target Species Modification Scale  
SIRGT56807WQ-2OMe TTL Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT57807WQ-2F TTL Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58807WQ-2MOE TTL Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT56807WQ-RB TTL Human Ribo-modified Inquiry
SIRGT57807WQ-BB TTL Human Backbone-modified Inquiry

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