siRNA, Anti-TYW1B, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT66480WQ-2OMe)

The product SIRGT66480WQ-2OMe is a type of small interfering RNA (siRNA) that targets TYW1B gene and regulates the expression of gene. The siRNA interferes with the expression of TYW1B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001145440.2
Alternative Names LINC00069; NCRNA00069; RSAFD2
Related Diseases Sorsby Fundus Dystrophy
Purification HPLC
Target Gene
Gene ID 441250
Uniprot ID Q6NUM6
Sub Cat Target Species Modification Scale  
SIRGT67480WQ-2F TYW1B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68480WQ-2MOE TYW1B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69480WQ-LNA TYW1B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT67480WQ-BB TYW1B Human Backbone-modified Inquiry

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