siRNA, Anti-UHRF1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76930WQ-2OMe)

The product SIRGT76930WQ-2OMe is a type of small interfering RNA (siRNA) that targets UHRF1 gene and regulates the expression of gene. The siRNA interferes with the expression of UHRF1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_013282.4
Alternative Names ICBP90; Np95; RNF106; TDRD22; hNP95; hUHRF1; huNp95
Related Diseases Colorectal Cancer
Purification HPLC
Target Gene
Gene ID 29128
Uniprot ID Q96T88
Sub Cat Target Species Modification Scale  
SIRGT77930WQ-2F UHRF1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78930WQ-2MOE UHRF1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79930WQ-LNA UHRF1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76930WQ-RB UHRF1 Human Ribo-modified Inquiry
SIRGT77930WQ-BB UHRF1 Human Backbone-modified Inquiry

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