siRNA, Anti-VKORC1L1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56950WQ-2OMe)

The product SIRGT56950WQ-2OMe is a type of small interfering RNA (siRNA) that targets VKORC1L1 gene and regulates the expression of gene. The siRNA interferes with the expression of VKORC1L1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001284342.2
Related Diseases Vitamin K Deficiency Bleeding
Purification HPLC
Target Gene
Gene ID 154807
Uniprot ID Q8N0U8
Sub Cat Target Species Modification Scale  
SIRGT57950WQ-2F VKORC1L1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58950WQ-2MOE VKORC1L1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT59950WQ-LNA VKORC1L1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT56950WQ-RB VKORC1L1 Human Ribo-modified Inquiry
SIRGT57950WQ-BB VKORC1L1 Human Backbone-modified Inquiry

Related Products