siRNA, Anti-ZFYVE27, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT51807WQ-2OMe)

The product SIRGT51807WQ-2OMe is a type of small interfering RNA (siRNA) that targets ZFYVE27 gene and regulates the expression of gene. The siRNA interferes with the expression of ZFYVE27 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001002261.3
Alternative Names PROTRUDIN; SPG33
Related Diseases Spastic Paraplegia 33
Purification HPLC
Target Gene
Gene ID 118813
Uniprot ID Q5T4F4
Sub Cat Target Species Modification Scale  
SIRGT52807WQ-2F ZFYVE27 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53807WQ-2MOE ZFYVE27 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT51807WQ-RB ZFYVE27 Human Ribo-modified Inquiry
SIRGT52807WQ-BB ZFYVE27 Human Backbone-modified Inquiry

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