siRNA, Anti-ZNF483, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56010WQ-2OMe)

The product SIRGT56010WQ-2OMe is a type of small interfering RNA (siRNA) that targets ZNF483 gene and regulates the expression of gene. The siRNA interferes with the expression of ZNF483 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001007169.4
Alternative Names ZKSCAN16; ZSCAN48
Related Diseases Mitochondrial Complex I Deficiency
Purification HPLC
Target Gene
Gene ID 158399
Uniprot ID Q8TF39
Sub Cat Target Species Modification Scale  
SIRGT57010WQ-2F ZNF483 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58010WQ-2MOE ZNF483 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT59010WQ-LNA ZNF483 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT56010WQ-RB ZNF483 Human Ribo-modified Inquiry
SIRGT57010WQ-BB ZNF483 Human Backbone-modified Inquiry

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