siRNA, Anti-Akr1c18, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT81326WQ-2OMe)

The product SIRGT81326WQ-2OMe is a type of small interfering RNA (siRNA) that targets Akr1c18 gene and regulates the expression of gene. The siRNA interferes with the expression of Akr1c18 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001346535.1
Alternative Names AW146047
Related Diseases Polycystic Ovary Syndrome
Purification HPLC
Target Gene
Gene ID 105349
Uniprot ID Q8K023
Sub Cat Target Species Modification Scale  
SIRGT82326WQ-2F Akr1c18 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT83326WQ-2MOE Akr1c18 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT84326WQ-LNA Akr1c18 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT81326WQ-RB Akr1c18 Mouse Ribo-modified Inquiry
SIRGT82326WQ-BB Akr1c18 Mouse Backbone-modified Inquiry

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