siRNA, Anti-Akr7a5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT86264WQ-2OMe)

The product SIRGT86264WQ-2OMe is a type of small interfering RNA (siRNA) that targets Akr7a5 gene and regulates the expression of gene. The siRNA interferes with the expression of Akr7a5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_025337.3
Alternative Names 0610025K21Rik; Afar; Afar1; Akr7a2
Related Diseases Alzheimer's disease
Purification HPLC
Target Gene
Gene ID 110198
Uniprot ID Q8CG76
Sub Cat Target Species Modification Scale  
SIRGT87264WQ-2F Akr7a5 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT88264WQ-2MOE Akr7a5 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT89264WQ-LNA Akr7a5 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT86264WQ-RB Akr7a5 Mouse Ribo-modified Inquiry
SIRGT87264WQ-BB Akr7a5 Mouse Backbone-modified Inquiry

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