siRNA, Anti-Atp6v1b1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT86333WQ-RB)
The product SIRGT86333WQ-RB is a type of small interfering RNA (siRNA) that targets Atp6v1b1 gene and regulates the expression of gene. The siRNA interferes with the expression of Atp6v1b1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with Ribo modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_134157.2 |
| Alternative Names | AW208839; Atp6b1; D630003L15; D630030L16Rik; D630039P21Rik; Vpp-3; Vpp3 |
| Related Diseases | Autosomal recessive nonsyndromic deafness |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT01348WQ-2OMe | ATP6V1B1 | Human | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT02348WQ-2F | ATP6V1B1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT03348WQ-2MOE | ATP6V1B1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT04348WQ-LNA | ATP6V1B1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT86333WQ-2OMe | Atp6v1b1 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT87333WQ-2F | Atp6v1b1 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT88333WQ-2MOE | Atp6v1b1 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT89333WQ-LNA | Atp6v1b1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT01348WQ-RB | ATP6V1B1 | Human | Ribo-modified | ||
| SIRGT02348WQ-BB | ATP6V1B1 | Human | Backbone-modified | ||
| SIRGT87333WQ-BB | Atp6v1b1 | Mouse | Backbone-modified |
