siRNA, Anti-Btg1-ps2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT86661WQ-2OMe)
The product SIRGT86661WQ-2OMe is a type of small interfering RNA (siRNA) that targets Btg1-ps2 gene and regulates the expression of gene. The siRNA interferes with the expression of Btg1-ps2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001034856.2 |
| Alternative Names | 4930430D24Rik |
| Related Diseases | Acute myeloid leukemia |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT87661WQ-2F | Btg1-ps2 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT88661WQ-2MOE | Btg1-ps2 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT89661WQ-LNA | Btg1-ps2 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT86661WQ-RB | Btg1-ps2 | Mouse | Ribo-modified | ||
| SIRGT87661WQ-BB | Btg1-ps2 | Mouse | Backbone-modified |