siRNA, Anti-Capn8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT81151WQ-2OMe)

The product SIRGT81151WQ-2OMe is a type of small interfering RNA (siRNA) that targets Capn8 gene and regulates the expression of gene. The siRNA interferes with the expression of Capn8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001145806.1
Alternative Names nCL-2; nCL-2'
Related Diseases Hereditary Spastic Paraplegia
Purification HPLC
Target Gene
Gene ID 170725
Uniprot ID Q91VA3
Sub Cat Target Species Modification Scale  
SIRGT82151WQ-2F Capn8 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT83151WQ-2MOE Capn8 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT84151WQ-LNA Capn8 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT81151WQ-RB Capn8 Mouse Ribo-modified Inquiry
SIRGT82151WQ-BB Capn8 Mouse Backbone-modified Inquiry

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