siRNA, Anti-Dscaml1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT81108WQ-2OMe)

The product SIRGT81108WQ-2OMe is a type of small interfering RNA (siRNA) that targets Dscaml1 gene and regulates the expression of gene. The siRNA interferes with the expression of Dscaml1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001081270.1
Alternative Names 4921507G06Rik; 4930435C18Rik; BB239540; mKIAA1132
Related Diseases Down Syndrome
Purification HPLC
Target Gene
Gene ID 114873
Uniprot ID Q4VA61
Sub Cat Target Species Modification Scale  
SIRGT82108WQ-2F Dscaml1 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT83108WQ-2MOE Dscaml1 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT84108WQ-LNA Dscaml1 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT81108WQ-RB Dscaml1 Mouse Ribo-modified Inquiry
SIRGT82108WQ-BB Dscaml1 Mouse Backbone-modified Inquiry

Related Products