siRNA, Anti-Guf1, 2'-F/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT97423WQ-2F)
The product SIRGT97423WQ-2F is a type of small interfering RNA (siRNA) that targets Guf1 gene and regulates the expression of gene. The siRNA interferes with the expression of Guf1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_172711.3 |
| Alternative Names | 4631409J12; AA407526; EF-4 |
| Related Diseases | Early Infantile Epileptic Encephalopathy 40 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT98423WQ-2MOE | Guf1 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT99423WQ-LNA | Guf1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT97423WQ-BB | Guf1 | Mouse | Backbone-modified |
