siRNA, Anti-H2-M10.3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT86303WQ-2OMe)
The product SIRGT86303WQ-2OMe is a type of small interfering RNA (siRNA) that targets H2-M10.3 gene and regulates the expression of gene. The siRNA interferes with the expression of H2-M10.3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_201608.2 |
| Alternative Names | 5.3H |
| Related Diseases | Respiratory syncytial virus infectious disease |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT87303WQ-2F | H2-M10.3 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT88303WQ-2MOE | H2-M10.3 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT89303WQ-LNA | H2-M10.3 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT86303WQ-RB | H2-M10.3 | Mouse | Ribo-modified | ||
| SIRGT87303WQ-BB | H2-M10.3 | Mouse | Backbone-modified |
