siRNA, Anti-Mkl1, 2'-F/2'-OMe/2'-MOE/Backbone-modified(CAT#: SIRGT91581WQ-2OMe)

The product SIRGT91581WQ-2OMe is a type of small interfering RNA (siRNA) that targets Mkl1 gene and regulates the expression of gene. The siRNA interferes with the expression of Mkl1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_153049.3
Alternative Names AMKL; Bsac; Mal; Mrtf-A
Related Diseases Megakaryocytic Leukemia
Purification HPLC
Target Gene
Gene ID 223701
Uniprot ID Q8K4J6
Sub Cat Target Species Modification Scale  
SIRGT92581WQ-2F Mkl1 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT93581WQ-2MOE Mkl1 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT92581WQ-BB Mkl1 Mouse Backbone-modified Inquiry

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