siRNA, Anti-Nlrp1a, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT89670WQ-LNA)

The product SIRGT89670WQ-LNA is a type of small interfering RNA (siRNA) that targets Nlrp1a gene and regulates the expression of gene. The siRNA interferes with the expression of Nlrp1a gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001004142.2
Alternative Names CARD7; DEFCAP; Gm14; Gm15; NAC; Nalp1; Nalp1a; Nlrp1; PP1044
Related Diseases Vitiligo
Purification HPLC
Target Gene
Gene ID 195046
Uniprot ID Q2LKU9
Sub Cat Target Species Modification Scale  
SIRGT86670WQ-2OMe Nlrp1a Mouse 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT87670WQ-2F Nlrp1a Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT88670WQ-2MOE Nlrp1a Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT86670WQ-RB Nlrp1a Mouse Ribo-modified Inquiry
SIRGT87670WQ-BB Nlrp1a Mouse Backbone-modified Inquiry

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