siRNA, Anti-Poglut1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT93415WQ-2MOE)

The product SIRGT93415WQ-2MOE is a type of small interfering RNA (siRNA) that targets Poglut1 gene and regulates the expression of gene. The siRNA interferes with the expression of Poglut1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_172380.4
Alternative Names 9630046K23Rik; Clp46; Ktelc1; Rumi
Related Diseases Dowling-Degos Disease
Purification HPLC
Target Gene
Gene ID 224143
Uniprot ID Q8BYB9
Sub Cat Target Species Modification Scale  
SIRGT91415WQ-2OMe Poglut1 Mouse 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT92415WQ-2F Poglut1 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT94415WQ-LNA Poglut1 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT91415WQ-RB Poglut1 Mouse Ribo-modified Inquiry
SIRGT92415WQ-BB Poglut1 Mouse Backbone-modified Inquiry

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