siRNA, Anti-Pomt1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT81821WQ-2OMe)

The product SIRGT81821WQ-2OMe is a type of small interfering RNA (siRNA) that targets Pomt1 gene and regulates the expression of gene. The siRNA interferes with the expression of Pomt1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_145145.1
Alternative Names AI505244
Related Diseases Muscular Dystrophy-Dystroglycanopathy
Purification HPLC
Target Gene
Gene ID 99011
Uniprot ID Q8R2R1
Sub Cat Target Species Modification Scale  
SIRGT31929WQ-2OMe POMT1 Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT32929WQ-2F POMT1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33929WQ-2MOE POMT1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34929WQ-LNA POMT1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT82821WQ-2F Pomt1 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT83821WQ-2MOE Pomt1 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT84821WQ-LNA Pomt1 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT31929WQ-RB POMT1 Human Ribo-modified Inquiry
SIRGT81821WQ-RB Pomt1 Mouse Ribo-modified Inquiry
SIRGT32929WQ-BB POMT1 Human Backbone-modified Inquiry
SIRGT82821WQ-BB Pomt1 Mouse Backbone-modified Inquiry

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