siRNA, Anti-septin 9, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT96881WQ-2OMe)
The product SIRGT96881WQ-2OMe is a type of small interfering RNA (siRNA) that targets septin 9 gene and regulates the expression of gene. The siRNA interferes with the expression of septin 9 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_017380.2 |
| Alternative Names | MSF1; Msf; PNUTL4; Sint1 |
| Related Diseases | Brachial Plexus Neuritis |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT97881WQ-2F | septin 9 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT98881WQ-2MOE | septin 9 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT99881WQ-LNA | septin 9 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT96881WQ-RB | septin 9 | Mouse | Ribo-modified | ||
| SIRGT97881WQ-BB | septin 9 | Mouse | Backbone-modified |