siRNA, Anti-Tmem250-ps, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT86187WQ-2OMe)
The product SIRGT86187WQ-2OMe is a type of small interfering RNA (siRNA) that targets Tmem250-ps gene and regulates the expression of gene. The siRNA interferes with the expression of Tmem250-ps gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001256521.1 |
| Alternative Names | AI551216; C330006A16Rik |
| Purification | HPLC |
| Target Gene | |
|---|---|
| Gene ID | 109299 |
| Uniprot ID | A0A571BES4 |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT87187WQ-2F | Tmem250-ps | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT88187WQ-2MOE | Tmem250-ps | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT89187WQ-LNA | Tmem250-ps | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT86187WQ-RB | Tmem250-ps | Mouse | Ribo-modified | ||
| SIRGT87187WQ-BB | Tmem250-ps | Mouse | Backbone-modified |