siRNA, Anti-Wnk1, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT98540WQ-2MOE)
The product SIRGT98540WQ-2MOE is a type of small interfering RNA (siRNA) that targets Wnk1 gene and regulates the expression of gene. The siRNA interferes with the expression of Wnk1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_198703.3 |
| Alternative Names | 6430573H23Rik; EG406236; Hsn2; Prkwnk1; mKIAA0344 |
| Related Diseases | Transient Cerebral Ischemia |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT96540WQ-2OMe | Wnk1 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT97540WQ-2F | Wnk1 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT99540WQ-LNA | Wnk1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT97540WQ-BB | Wnk1 | Mouse | Backbone-modified |