siRNA, Anti-AANAT, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01008WQ-2OMe)

The product SIRGT01008WQ-2OMe is a type of small interfering RNA (siRNA) that targets AANAT gene and regulates the expression of gene. The siRNA interferes with the expression of AANAT genes with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001088.2; NM_001166579.1
Alternative Names DSPS; SNAT
Related Diseases Dissociative Amnesia, Delayed Sleep Phase Disorder
Purification HPLC
Target Gene
Gene ID 15
Uniprot ID Q16613
Sub Cat Target Species Modification Scale  
SIRGT02008WQ-2F AANAT Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03008WQ-2MOE AANAT Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01008WQ-RB AANAT Human Ribo-modified Inquiry
SIRGT02008WQ-BB AANAT Human Backbone-modified Inquiry

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