siRNA, Anti-ABCC2, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01846WQ-2OMe)

The product SIRGT01846WQ-2OMe is a type of small interfering RNA (siRNA) that targets ABCC2 gene and regulates the expression of gene. The siRNA interferes with the expression of ABCC2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000392.4
Alternative Names ABC30; CMOAT; DJS; MRP2; cMRP
Related Diseases Dubin-Johnson syndrome (DJS)
Purification HPLC
Target Gene
Gene ID 1244
Uniprot ID Q92887
Sub Cat Target Species Modification Scale  
SIRGT02846WQ-2F ABCC2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03846WQ-2MOE ABCC2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01846WQ-RB ABCC2 Human Ribo-modified Inquiry
SIRGT02846WQ-BB ABCC2 Human Backbone-modified Inquiry

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