siRNA, Anti-ADRB1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01102WQ-2OMe)

The product SIRGT01102WQ-2OMe is a type of small interfering RNA (siRNA) that targets ADRB1 gene and regulates the expression of gene. The siRNA interferes with the expression of ADRB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000684.2
Alternative Names ADRB1R; B1AR; BETA1AR; RHR
Related Diseases Resting Heart Rate, Short Sleep
Purification HPLC
Target Gene
Gene ID 153
Uniprot ID P08588
Sub Cat Target Species Modification Scale  
SIRGT02102WQ-2F ADRB1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03102WQ-2MOE ADRB1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04102WQ-LNA ADRB1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01102WQ-RB ADRB1 Human Ribo-modified Inquiry
SIRGT02102WQ-BB ADRB1 Human Backbone-modified Inquiry

Related Products