siRNA, Anti-AGT, 2'-F/2'-OMe/2'-MOE/Ribo-modified(CAT#: SIRGT01122WQ-2OMe)

The product SIRGT01122WQ-2OMe is a type of small interfering RNA (siRNA) that targets AGT gene and regulates the expression of gene. The siRNA interferes with the expression of AGT gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000029.3
Alternative Names ANHU; SERPINA8; hFLT1
Related Diseases Renal Tubular Dysgenesis, Hypertension
Purification HPLC
Target Gene
Gene ID 183
Uniprot ID P01019
Sub Cat Target Species Modification Scale  
SIRGT02122WQ-2F AGT Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03122WQ-2MOE AGT Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01122WQ-RB AGT Human Ribo-modified Inquiry

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