siRNA, Anti-AKAP12, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT31132WQ-2OMe)

The product SIRGT31132WQ-2OMe is a type of small interfering RNA (siRNA) that targets AKAP12 gene and regulates the expression of gene. The siRNA interferes with the expression of AKAP12 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005100.3; NM_144497.2
Alternative Names AKAP250; SSeCKS
Related Diseases Myasthenia Gravis
Purification HPLC
Target Gene
Gene ID 9590
Uniprot ID Q02952
Sub Cat Target Species Modification Scale  
SIRGT32132WQ-2F AKAP12 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33132WQ-2MOE AKAP12 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT31132WQ-RB AKAP12 Human Ribo-modified Inquiry
SIRGT32132WQ-BB AKAP12 Human Backbone-modified Inquiry

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