siRNA, Anti-AP1S1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01809WQ-2OMe)

The product SIRGT01809WQ-2OMe is a type of small interfering RNA (siRNA) that targets AP1S1 gene and regulates the expression of gene. The siRNA interferes with the expression of AP1S1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001283.4
Alternative Names AP19; CLAPS1; EKV3; MEDNIK; SIGMA1A
Related Diseases Mental Retardation, Enteropathy, Deafness
Purification HPLC
Target Gene
Gene ID 1174
Uniprot ID P61966
Sub Cat Target Species Modification Scale  
SIRGT02809WQ-2F AP1S1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03809WQ-2MOE AP1S1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04809WQ-LNA AP1S1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01809WQ-RB AP1S1 Human Ribo-modified Inquiry
SIRGT02809WQ-BB AP1S1 Human Backbone-modified Inquiry

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