siRNA, Anti-AP4E1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT36950WQ-2OMe)

The product SIRGT36950WQ-2OMe is a type of small interfering RNA (siRNA) that targets AP4E1 gene and regulates the expression of gene. The siRNA interferes with the expression of AP4E1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001252127.1
Alternative Names CPSQ4; SPG51; STUT1
Related Diseases Spastic Paraplegia 51, Autosomal Recessive
Purification HPLC
Target Gene
Gene ID 23431
Uniprot ID Q9UPM8
Sub Cat Target Species Modification Scale  
SIRGT38950WQ-2MOE AP4E1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT87027WQ-2F Ap4e1 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT36950WQ-RB AP4E1 Human Ribo-modified Inquiry
SIRGT37950WQ-BB AP4E1 Human Backbone-modified Inquiry
SIRGT87027WQ-BB Ap4e1 Mouse Backbone-modified Inquiry

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