siRNA, Anti-APOC3, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01230WQ-2OMe)

The product SIRGT01230WQ-2OMe is a type of small interfering RNA (siRNA) that targets APOC3 gene and regulates the expression of gene. The siRNA interferes with the expression of APOC3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000040.2
Alternative Names APOCIII
Related Diseases Apolipoprotein C-Iii Deficiency, Coronary Heart Disease
Purification HPLC
Target Gene
Gene ID 345
Uniprot ID P02656
Sub Cat Target Species Modification Scale  
SIRGT02230WQ-2F APOC3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03230WQ-2MOE APOC3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01230WQ-RB APOC3 Human Ribo-modified Inquiry
SIRGT02230WQ-BB APOC3 Human Backbone-modified Inquiry

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