siRNA, Anti-AQP5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01245WQ-2OMe)

The product SIRGT01245WQ-2OMe is a type of small interfering RNA (siRNA) that targets AQP5 gene and regulates the expression of gene. The siRNA interferes with the expression of AQP5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001651.3
Alternative Names AQP-5; PPKB
Related Diseases Palmoplantar Keratoderma
Purification HPLC
Target Gene
Gene ID 362
Uniprot ID P55064
Sub Cat Target Species Modification Scale  
SIRGT02245WQ-2F AQP5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03245WQ-2MOE AQP5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04245WQ-LNA AQP5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01245WQ-RB AQP5 Human Ribo-modified Inquiry
SIRGT02245WQ-BB AQP5 Human Backbone-modified Inquiry

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