siRNA, Anti-AQP7, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT02247WQ-2F)
The product SIRGT02247WQ-2F is a type of small interfering RNA (siRNA) that targets AQP7 gene and regulates the expression of gene. The siRNA interferes with the expression of AQP7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001170.2; NM_001318156.1; NM_001318157.1; NM_001318158.1 |
| Alternative Names | AQP7L; AQPap; GLYCQTL |
| Related Diseases | Glycerol Quantitative Trait Locus, Body Mass Index Quantitative Trait Locus |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT03247WQ-2MOE | AQP7 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT04247WQ-LNA | AQP7 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT01247WQ-RB | AQP7 | Human | Ribo-modified | ||
| SIRGT02247WQ-BB | AQP7 | Human | Backbone-modified |