siRNA, Anti-AQP8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01228WQ-2OMe)

The product SIRGT01228WQ-2OMe is a type of small interfering RNA (siRNA) that targets AQP8 gene and regulates the expression of gene. The siRNA interferes with the expression of AQP8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001169.2
Alternative Names AQP-8
Related Diseases Polyhydramnios, Diabetes Insipidus
Purification HPLC
Target Gene
Gene ID 343
Uniprot ID O94778
Sub Cat Target Species Modification Scale  
SIRGT02228WQ-2F AQP8 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03228WQ-2MOE AQP8 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04228WQ-LNA AQP8 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01228WQ-RB AQP8 Human Ribo-modified Inquiry
SIRGT02228WQ-BB AQP8 Human Backbone-modified Inquiry

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