siRNA, Anti-ARRB2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01283WQ-2OMe)
The product SIRGT01283WQ-2OMe is a type of small interfering RNA (siRNA) that targets ARRB2 gene and regulates the expression of gene. The siRNA interferes with the expression of ARRB2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001257328.1; NM_001257329.1; NM_001257330.1; NM_001257331.1; NM_001330064.1; NM_004313.3; NM_199004.1 |
| Alternative Names | ARB2; ARR2; BARR2 |
| Related Diseases | Whim Syndrome, Cecum Lymphoma |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT02283WQ-2F | ARRB2 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT03283WQ-2MOE | ARRB2 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT04283WQ-LNA | ARRB2 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT91538WQ-2OMe | Arrb2 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT92538WQ-2F | Arrb2 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT93538WQ-2MOE | Arrb2 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT94538WQ-LNA | Arrb2 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT01283WQ-RB | ARRB2 | Human | Ribo-modified | ||
| SIRGT91538WQ-RB | Arrb2 | Mouse | Ribo-modified | ||
| SIRGT02283WQ-BB | ARRB2 | Human | Backbone-modified | ||
| SIRGT92538WQ-BB | Arrb2 | Mouse | Backbone-modified |
