siRNA, Anti-ARSB, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01285WQ-2OMe)

The product SIRGT01285WQ-2OMe is a type of small interfering RNA (siRNA) that targets ARSB gene and regulates the expression of gene. The siRNA interferes with the expression of ARSB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000046.4; NM_198709.2
Alternative Names ASB; G4S; MPS6
Related Diseases Mucopolysaccharidosis
Purification HPLC
Target Gene
Gene ID 411
Uniprot ID P15848
Sub Cat Target Species Modification Scale  
SIRGT02285WQ-2F ARSB Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03285WQ-2MOE ARSB Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04285WQ-LNA ARSB Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01285WQ-RB ARSB Human Ribo-modified Inquiry
SIRGT02285WQ-BB ARSB Human Backbone-modified Inquiry

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