siRNA, Anti-ATP1A4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01322WQ-2OMe)

The product SIRGT01322WQ-2OMe is a type of small interfering RNA (siRNA) that targets ATP1A4 gene and regulates the expression of gene. The siRNA interferes with the expression of ATP1A4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001001734.1; NM_144699.3
Alternative Names ATP1A1; ATP1AL2
Related Diseases Conn's Syndrome, Hypomagnesemia
Purification HPLC
Target Gene
Gene ID 480
Uniprot ID Q13733
Sub Cat Target Species Modification Scale  
SIRGT02322WQ-2F ATP1A4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03322WQ-2MOE ATP1A4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04322WQ-LNA ATP1A4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01322WQ-RB ATP1A4 Human Ribo-modified Inquiry
SIRGT02322WQ-BB ATP1A4 Human Backbone-modified Inquiry

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