siRNA, Anti-ATP1B2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01324WQ-2OMe)

The product SIRGT01324WQ-2OMe is a type of small interfering RNA (siRNA) that targets ATP1B2 gene and regulates the expression of gene. The siRNA interferes with the expression of ATP1B2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001303263.1; NM_001678.4
Alternative Names AMOG
Related Diseases Familial Hemiplegic Migraine, Retinoschisis
Purification HPLC
Target Gene
Gene ID 482
Uniprot ID P14415
Sub Cat Target Species Modification Scale  
SIRGT02324WQ-2F ATP1B2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03324WQ-2MOE ATP1B2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04324WQ-LNA ATP1B2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01324WQ-RB ATP1B2 Human Ribo-modified Inquiry
SIRGT02324WQ-BB ATP1B2 Human Backbone-modified Inquiry

Related Products