siRNA, Anti-ATP2B1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT01329WQ-2OMe)

The product SIRGT01329WQ-2OMe is a type of small interfering RNA (siRNA) that targets ATP2B1 gene and regulates the expression of gene. The siRNA interferes with the expression of ATP2B1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001001323.1; NM_001682.2
Alternative Names PMCA1; PMCA1kb
Related Diseases Nephrotic Syndrome, Brachyolmia Type 4
Purification HPLC
Target Gene
Gene ID 490
Uniprot ID P20020
Sub Cat Target Species Modification Scale  
SIRGT02329WQ-2F ATP2B1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03329WQ-2MOE ATP2B1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04329WQ-LNA ATP2B1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01329WQ-RB ATP2B1 Human Ribo-modified Inquiry

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