siRNA, Anti-ATP6V1F, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26915WQ-2OMe)

The product SIRGT26915WQ-2OMe is a type of small interfering RNA (siRNA) that targets ATP6V1F gene and regulates the expression of gene. The siRNA interferes with the expression of ATP6V1F gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001198909.1; NM_004231.3
Alternative Names ATP6S14; VATF; Vma7
Related Diseases Hermansky-Pudlak Syndrome
Purification HPLC
Target Gene
Gene ID 9296
Uniprot ID Q16864
Sub Cat Target Species Modification Scale  
SIRGT27915WQ-2F ATP6V1F Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28915WQ-2MOE ATP6V1F Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29915WQ-LNA ATP6V1F Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26915WQ-RB ATP6V1F Human Ribo-modified Inquiry
SIRGT27915WQ-BB ATP6V1F Human Backbone-modified Inquiry

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