siRNA, Anti-AUH, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT02362WQ-2F)
The product SIRGT02362WQ-2F is a type of small interfering RNA (siRNA) that targets AUH gene and regulates the expression of gene. The siRNA interferes with the expression of AUH gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001306190.1; NM_001351431.1; NM_001351432.1; NM_001351433.1; NM_001698.2 |
| Related Diseases | 3-Methylglutaconic Aciduria |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT03362WQ-2MOE | AUH | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT04362WQ-LNA | AUH | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT01362WQ-RB | AUH | Human | Ribo-modified | ||
| SIRGT02362WQ-BB | AUH | Human | Backbone-modified |
