siRNA, Anti-B2M, 2'-F/2'-OMe/Ribo/Backbone-modified(CAT#: SIRGT01371WQ-2OMe)

The product SIRGT01371WQ-2OMe is a type of small interfering RNA (siRNA) that targets B2M gene and regulates the expression of gene. The siRNA interferes with the expression of B2M gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004048.2
Alternative Names IMD43
Related Diseases Immunodeficiency, Amyloidosis, Familial Visceral
Purification HPLC
Target Gene
Gene ID 567
Uniprot ID P61769
Sub Cat Target Species Modification Scale  
SIRGT02371WQ-2F B2M Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT01371WQ-RB B2M Human Ribo-modified Inquiry
SIRGT02371WQ-BB B2M Human Backbone-modified Inquiry

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