siRNA, Anti-BPI, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01450WQ-2OMe)

The product SIRGT01450WQ-2OMe is a type of small interfering RNA (siRNA) that targets BPI gene and regulates the expression of gene. The siRNA interferes with the expression of BPI gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001725.2
Alternative Names BPIFD1; rBPI
Related Diseases Meningococcemia, Reactive Arthritis
Purification HPLC
Target Gene
Gene ID 671
Uniprot ID P17213
Sub Cat Target Species Modification Scale  
SIRGT02450WQ-2F BPI Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03450WQ-2MOE BPI Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04450WQ-LNA BPI Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01450WQ-RB BPI Human Ribo-modified Inquiry
SIRGT02450WQ-BB BPI Human Backbone-modified Inquiry

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