siRNA, Anti-BRD3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26126WQ-2OMe)

The product SIRGT26126WQ-2OMe is a type of small interfering RNA (siRNA) that targets BRD3 gene and regulates the expression of gene. The siRNA interferes with the expression of BRD3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_007371.3
Alternative Names ORFX; RING3L
Related Diseases Foodborne Botulism, Salivary Gland Carcinoma
Purification HPLC
Target Gene
Gene ID 8019
Uniprot ID Q15059
Sub Cat Target Species Modification Scale  
SIRGT27126WQ-2F BRD3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28126WQ-2MOE BRD3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29126WQ-LNA BRD3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26126WQ-RB BRD3 Human Ribo-modified Inquiry
SIRGT27126WQ-BB BRD3 Human Backbone-modified Inquiry

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