siRNA, Anti-BRD4, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT36978WQ-2OMe)

The product SIRGT36978WQ-2OMe is a type of small interfering RNA (siRNA) that targets BRD4 gene and regulates the expression of gene. The siRNA interferes with the expression of BRD4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001330384.1
Alternative Names CAP; HUNK1; HUNKI; MCAP
Related Diseases Exophthalmic Ophthalmoplegia
Purification HPLC
Target Gene
Gene ID 23476
Uniprot ID O60885
Sub Cat Target Species Modification Scale  
SIRGT37978WQ-2F BRD4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT39978WQ-LNA BRD4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36978WQ-RB BRD4 Human Ribo-modified Inquiry
SIRGT37978WQ-BB BRD4 Human Backbone-modified Inquiry

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