siRNA, Anti-BRIP1, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT46738WQ-2OMe)

The product SIRGT46738WQ-2OMe is a type of small interfering RNA (siRNA) that targets BRIP1 gene and regulates the expression of gene. The siRNA interferes with the expression of BRIP1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032043.2
Alternative Names BACH1; FANCJ; OF
Related Diseases Breast Cancer
Purification HPLC
Target Gene
Gene ID 83990
Uniprot ID Q9BX63
Sub Cat Target Species Modification Scale  
SIRGT102365WQ-2F Brip1 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT104365WQ-LNA Brip1 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT46738WQ-RB BRIP1 Human Ribo-modified Inquiry
SIRGT47738WQ-BB BRIP1 Human Backbone-modified Inquiry
SIRGT102365WQ-BB Brip1 Mouse Backbone-modified Inquiry

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