siRNA, Anti-BRS3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01457WQ-2OMe)

The product SIRGT01457WQ-2OMe is a type of small interfering RNA (siRNA) that targets BRS3 gene and regulates the expression of gene. The siRNA interferes with the expression of BRS3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001727.1
Alternative Names BB3; BB3R
Related Diseases Lung Cancer, Brugada Syndrome
Purification HPLC
Target Gene
Gene ID 680
Uniprot ID P32247
Sub Cat Target Species Modification Scale  
SIRGT02457WQ-2F BRS3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03457WQ-2MOE BRS3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04457WQ-LNA BRS3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01457WQ-RB BRS3 Human Ribo-modified Inquiry
SIRGT02457WQ-BB BRS3 Human Backbone-modified Inquiry

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