siRNA, Anti-CAD, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01532WQ-2OMe)

The product SIRGT01532WQ-2OMe is a type of small interfering RNA (siRNA) that targets CAD gene and regulates the expression of gene. The siRNA interferes with the expression of CAD gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001306079.1; NM_004341.4
Alternative Names CDG1Z; EIEE50; GATD4
Related Diseases Epileptic Encephalopathy, Paramyloidosis
Purification HPLC
Target Gene
Gene ID 790
Uniprot ID P27708
Sub Cat Target Species Modification Scale  
SIRGT02532WQ-2F CAD Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03532WQ-2MOE CAD Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04532WQ-LNA CAD Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01532WQ-RB CAD Human Ribo-modified Inquiry
SIRGT02532WQ-BB CAD Human Backbone-modified Inquiry

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